Structure of PDB 5tms Chain B

Receptor sequence
>5tmsB (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
KKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLAD
RELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK
LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSI
ILLNSGVYTTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLA
QLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5tms Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainB
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 Q375 V376 L379 E380 D538 L539 E542 I57 K61 L71 Q74 V75 L78 E79 D233 L234 E237
BS02 7FG B A350 E353 W383 M421 L525 A49 E52 W82 M120 L220
External links
PDB RCSB:5tms, PDBe:5tms, PDBj:5tms
PDBsum5tms
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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