Structure of PDB 5tmo Chain B

Receptor sequence
>5tmoB (length=239) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5tmo Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainB
Resolution2.172 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 Q375 V376 E380 D538 L539 E542 I54 K58 L68 Q71 V72 E76 D229 L230 E233
BS02 7M1 B M343 T347 A350 E353 L387 F404 M421 I424 F425 L540 M39 T43 A46 E49 L83 F100 M117 I120 F121 L231
External links
PDB RCSB:5tmo, PDBe:5tmo, PDBj:5tmo
PDBsum5tmo
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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