Structure of PDB 5tm3 Chain B

Receptor sequence
>5tm3B (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR
ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKL
LFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII
LLNSGVYTFTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLA
QLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5tm3 Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainB
Resolution2.194 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 E380 D538 L539 E542 I56 K60 L70 V74 E78 D233 L234 E237
BS02 7EN B L346 T347 L349 A350 E353 L387 M388 F404 M421 L525 L44 T45 L47 A48 E51 L85 M86 F102 M119 L220
External links
PDB RCSB:5tm3, PDBe:5tm3, PDBj:5tm3
PDBsum5tm3
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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