Structure of PDB 5tlt Chain B

Receptor sequence
>5tltB (length=240) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLL
ILSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB5tlt Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainB
Resolution1.903 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 E380 D538 L539 E542 M543 I54 K58 L68 V72 L75 E76 D229 L230 E233 M234
BS02 7ED B M343 A350 E353 L387 F404 M421 H524 L525 M528 M39 A46 E49 L83 F100 M117 H215 L216 M219
External links
PDB RCSB:5tlt, PDBe:5tlt, PDBj:5tlt
PDBsum5tlt
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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