Structure of PDB 5tkm Chain B

Receptor sequence
>5tkmB (length=184) Species: 9606 (Homo sapiens) [Search protein sequence]
NPMERMDRDTFYDNFENEPILSGRSYTWLCYEVKIKRGRSNLLWDTGVFR
GQVYFKPQYHAEMCFLSWFCGNQLPADKCFQITWFVSWTPCPDCVAKLAE
FLSEHPNVTLTISAARLYYYSERDYRRALCRLSQAGARVKIMDYEEFAYC
WENFVDNEGQQFMPWYKFDENYAFLHRTLKEILR
3D structure
PDB5tkm Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation.
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.38: single-stranded DNA cytosine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H66 C97 C100 H60 C91 C94
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5tkm, PDBe:5tkm, PDBj:5tkm
PDBsum5tkm
PubMed28575276
UniProtQ9UH17|ABC3B_HUMAN DNA dC->dU-editing enzyme APOBEC-3B (Gene Name=APOBEC3B)

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