Structure of PDB 5t6p Chain B

Receptor sequence

>5t6pB (length=206) Species: 10090 (Mus musculus) [Search protein sequence]

VKLVESGGGLVAPGGSLKLSCAASGFTFSSYPMSWVRQTPEKRLEWVAYI
NNGGGNPYYPDTVKGRFTISRDNAKNTLYLQMSSLKSEDTAIYYCIRQYY
GFDYWGQGTTLTVSSAKTTPPSVYPLAPMVTLGCLVKGYFPEPVTVTWNS
GSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSETVTCNVAHPASSTKV
DKKIVP

3D structure

PDB

5t6p Glycosylation of MUC1 influences the binding of a therapeutic antibody by altering the conformational equilibrium of the antigen.

Chain

Resolution

1.97 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	Y50 Y59 Q99 Y100 Y101 G102 F103	Y49 Y58 Q98 Y99 Y100 G101 F102

External links

PDB	RCSB:5t6p, PDBe:5t6p, PDBj:5t6p
PDBsum	5t6p
PubMed	28025250

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