Structure of PDB 5t4m Chain B

Receptor sequence
>5t4mB (length=346) Species: 9606 (Homo sapiens) [Search protein sequence]
ASPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQP
GILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD
NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNL
TSPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTQTGITRYLTLLQPVD
REEQQTYTFSITAFDGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYT
DMRPGDSVIQLTAVDADEGSNGEITYEILVGAQGDFIINKTTGLITIAPG
VEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRF
3D structure
PDB5t4m A Partial Calcium-Free Linker Confers Flexibility to Inner-Ear Protocadherin-15.
ChainB
Resolution2.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E385 E451 D480 A481 D483 D516 E136 E202 D231 A232 D234 D267
BS02 CA B N482 N484 D514 D516 N520 D566 N233 N235 D265 D267 N271 D317
BS03 CA B E385 D449 E451 D483 E136 D200 E202 D234
BS04 CA B N368 Q370 D409 D411 D464 N119 Q121 D160 D162 D215
BS05 CA B D366 E367 N369 D411 D117 E118 N120 D162
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5t4m, PDBe:5t4m, PDBj:5t4m
PDBsum5t4m
PubMed28238533
UniProtQ96QU1|PCD15_HUMAN Protocadherin-15 (Gene Name=PCDH15)

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