Structure of PDB 5s9q Chain B

Receptor sequence
>5s9qB (length=128) Species: 9606 (Homo sapiens) [Search protein sequence]
GHMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAV
KLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYN
KPGDDIVLMAEALEKLFLQKINELPTEE
3D structure
PDB5s9q Discovery and Preclinical Pharmacology of an Oral Bromodomain and Extra-Terminal (BET) Inhibitor Using Scaffold-Hopping and Structure-Guided Drug Design.
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YW7 B W81 P82 F83 Q85 K91 L92 I146 M149 W41 P42 F43 Q45 K51 L52 I106 M109
External links
PDB RCSB:5s9q, PDBe:5s9q, PDBj:5s9q
PDBsum5s9q
PubMed34543572
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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