Structure of PDB 5qu2 Chain B

Receptor sequence
>5qu2B (length=56) Species: 9606 (Homo sapiens) [Search protein sequence]
EEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVP
SNYVER
3D structure
PDB5qu2 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
ChainB
Resolution1.04 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F9 E18 K34 S35 W36 F48 N52 Y53 F9 E18 K34 S35 W36 F48 N52 Y53
External links
PDB RCSB:5qu2, PDBe:5qu2, PDBj:5qu2
PDBsum5qu2
PubMed32317279
UniProtP16333|NCK1_HUMAN SH2/SH3 adapter protein NCK1 (Gene Name=NCK1)

[Back to BioLiP]