Structure of PDB 5ona Chain B

Receptor sequence
>5onaB (length=273) Species: 9606 (Homo sapiens) [Search protein sequence]
GPHMLEREKIYQWINELSSPETRENALLELSKKRESVPDLAPMLWHSFGT
IAALLQEIVNIYPSINPPTLTAHQSNRVCNALALLQCVASHPETRSAFLA
AHIPLFLYPFLHTVSKTRPFEYLRLTSLGVIGALVKTDEQEVINFLLTTE
IIPLCLRIMESGSELSKTVATFILQKILLDDTGLAYICQTYERFSHVAMI
LGKMVLQLSKEPSARLLKHVVRCYLRLSDNPRAREALRQCLPDQLKDTTF
AQVLKDDTTTKRWLAQLVKNLQE
3D structure
PDB5ona DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B N88 R130 E133 Y134 L137 T138 G141 G144 F184 H231 N76 R118 E121 Y122 L125 T126 G129 G132 F172 H219
Gene Ontology
Biological Process
GO:0006402 mRNA catabolic process
Cellular Component
GO:0030014 CCR4-NOT complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5ona, PDBe:5ona, PDBj:5ona
PDBsum5ona
PubMed29255063
UniProtQ92600|CNOT9_HUMAN CCR4-NOT transcription complex subunit 9 (Gene Name=CNOT9)

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