Structure of PDB 5olm Chain B

Receptor sequence
>5olmB (length=132) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGG
GSVCPVCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGE
RLHLFCEKDGKALCWVCAQSRKHRDHAMVPLE
3D structure
PDB5olm Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21.
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C16 C19 C36 C39 C19 C22 C39 C42
BS02 ZN B C31 H33 C51 C54 C34 H36 C54 C57
BS03 ZN B C92 H95 C111 C114 C95 H98 C114 C117
BS04 ZN B C103 D106 H120 H123 C106 D109 H123 H126
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:5olm, PDBe:5olm, PDBj:5olm
PDBsum5olm
PubMed29667579
UniProtP19474|RO52_HUMAN E3 ubiquitin-protein ligase TRIM21 (Gene Name=TRIM21)

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