Structure of PDB 5obg Chain B

Receptor sequence
>5obgB (length=208) Species: 6500 (Aplysia californica) [Search protein sequence]
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFFLQDIVKVDSSTNEVDL
VYYERQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAASSTRPVQVL
SPQIAVVTHDGSVMFSPAQRLSFMCDPTGVDSEEGVTCAVKFESWVYSGF
EIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYKGTGEPYIDVNLVV
KFRERRFF
3D structure
PDB5obg Engineering a surrogate human heteromeric alpha / beta glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SY9 B W164 V165 Y205 E210 Y212 W145 V146 Y186 E191 Y193 PDBbind-CN: -logKd/Ki=7.13,Kd=74.1nM
Gene Ontology
Molecular Function
GO:0004888 transmembrane signaling receptor activity
GO:0005216 monoatomic ion channel activity
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5obg, PDBe:5obg, PDBj:5obg
PDBsum5obg
PubMed31709057
UniProtQ8WSF8

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