Structure of PDB 5o5z Chain B

Receptor sequence
>5o5zB (length=449) Species: 2265 (Thermococcus litoralis) [Search protein sequence]
ESLKDRIRLWKRLYVNAFENALNAIPNVKGVLLAYNTNIDAIKYLDADDL
EKRVTEKGKEKVFEIIENPPEKISSIEELLGGILRSIKLGKAMEWFVESE
EVRRYLREWGWDELRIGGQAGIMANLLGGVYRIPTIVHVPQNPKLQAELF
VDGPIYVPVFEGNKLKLVHPKDAIAEEEELIHYIYEFPRGFQVFDVQAPR
ENRFIANADDYNARVYMRREFREGFEEITRNVELAIISGLQVLKEYYPDG
TTYKDVLDRVESHLNILNRYNVKSHFEFAYTANRRVREALVELLPKFTSV
GLNEVELASIMEIIGDEELAKEVLEGHIFSVIDAMNVLMDETGIERIHFH
TYGYYLALTQGGGRQLAFVPTKIVASPKSTVGIGDTISSSAFVSEFGGGG
GVRDALLFASLAAAAKAMKGNLERIEQIRDALSVPTNERAIVLEEELEK
3D structure
PDB5o5z Protein topology determines substrate-binding mechanism in homologous enzymes.
ChainB
Resolution2.441 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.-
2.7.1.147: ADP-specific glucose/glucosamine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC B D42 E96 H184 D387 D40 E94 H182 D385
BS02 AT4 B N305 H352 T353 V376 I385 G386 I389 N303 H350 T351 V374 I383 G384 I387
Gene Ontology
Molecular Function
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5o5z, PDBe:5o5z, PDBj:5o5z
PDBsum5o5z
PubMed30251675
UniProtQ7M537|GLKA_THELN ADP-dependent glucose/glucosamine kinase (Gene Name=glkA)

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