Structure of PDB 5o4y Chain B

Receptor sequence
>5o4yB (length=118) Species: 9606 (Homo sapiens) [Search protein sequence]
AFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQF
VHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMIS
YGGADYKRITVKVNAAYA
3D structure
PDB5o4y Bioactive Macrocyclic Inhibitors of the PD-1/PD-L1 Immune Checkpoint.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I54 Y56 N63 Q66 V68 D73 V76 R113 M115 Y123 I37 Y39 N46 Q49 V51 D56 V59 R96 M98 Y106
External links
PDB RCSB:5o4y, PDBe:5o4y, PDBj:5o4y
PDBsum5o4y
PubMed28881104
UniProtQ9NZQ7|PD1L1_HUMAN Programmed cell death 1 ligand 1 (Gene Name=CD274)

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