Structure of PDB 5o4f Chain B

Receptor sequence
>5o4fB (length=250) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RSLIVTTLLEEPFVMFRKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEI
RLVEDGKYGAQDDKGQWNGMVKELIDHKADLAVAPLTITHVREKAIDFSK
PFMTLGVSILYRKGTPIDSADDLAKQTKIEYGAVKDGATMTFFKKSKIST
FEKMWAFMSSKPSALVKNNEEGIQRTLTADYALLMESTTIEYITQRNCNL
TQIGGLIDSKGYGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGC
3D structure
PDB5o4f Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8VE B Y61 P88 T90 R95 A141 T142 E189 Y58 P85 T87 R92 A138 T139 E186 MOAD: Ki=208uM
PDBbind-CN: -logKd/Ki=6.68,Ki=208nM
BS02 ZN B D240 H243 D237 H240
BS03 ZN B E42 K241 E39 K238
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5o4f, PDBe:5o4f, PDBj:5o4f
PDBsum5o4f
PubMed28691798
UniProtP42264|GRIK3_RAT Glutamate receptor ionotropic, kainate 3 (Gene Name=Grik3)

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