Structure of PDB 5nl1 Chain B

Receptor sequence
>5nl1B (length=142) Species: 10090 (Mus musculus) [Search protein sequence]
PLTSAQQALTGTINSSMQAVQAAQATLDDFETLPPLGQDAASKAWRKNKM
DESKHEIHSQVDAITAGTASVVNLTAGDPAETDYTAVGCAVTTISSNLTE
MSRGVKLLAALLEDEGGNGRPLLQAAKGLAGAVSELLRSAQP
3D structure
PDB5nl1 Shigella IpaA Binding to Talin Stimulates Filopodial Capture and Cell Adhesion.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B K540 V547 T554 V558 T561 P607 A611 A612 L615 A618 E621 L622 S625 K54 V61 T68 V72 T75 P121 A125 A126 L129 A132 E135 L136 S139
BS02 peptide B S501 Q504 A508 S15 Q18 A22
BS03 peptide B N559 E567 N73 E81
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
Cellular Component
GO:0001726 ruffle
GO:0005925 focal adhesion

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:5nl1, PDBe:5nl1, PDBj:5nl1
PDBsum5nl1
PubMed30673614
UniProtP26039|TLN1_MOUSE Talin-1 (Gene Name=Tln1)

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