Structure of PDB 5njj Chain B

Receptor sequence
>5njjB (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
TDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFF
GKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSY
ICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLER
3D structure
PDB5njj A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B E112 K113 V114 S115 F116 C117 R132 S155 H156 G159 F162 E83 K84 V85 S86 F87 C88 R103 S126 H127 G130 F133
External links
PDB RCSB:5njj, PDBe:5njj, PDBj:5njj
PDBsum5njj
PubMed29269425
UniProtP49757|NUMB_HUMAN Protein numb homolog (Gene Name=NUMB)

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