Structure of PDB 5nj8 Chain B

Receptor sequence
>5nj8B (length=174) Species: 10090 (Mus musculus) [Search protein sequence]
DKERLARENHSEIERRRRNKMTAYITELSDMVPTCPDKLTILRMAVSHMK
SLRGSYKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPVLN
QPQSEWFGSTLYDQVHPDDVDKLREQLSTSSRRSFICRMRCHFVVVHCTG
YIKAWPDDDPEAKFCLVAIGRLQV
3D structure
PDB5nj8 Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation.
ChainB
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B E98 R101 E14 R17 PDBbind-CN: Kd=90nM
BS02 dna B R88 H94 R102 D127 K128 R4 H10 R18 D37 K38 PDBbind-CN: Kd=90nM
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5nj8, PDBe:5nj8, PDBj:5nj8
PDBsum5nj8
PubMed28602820
UniProtP27540|ARNT_HUMAN Aryl hydrocarbon receptor nuclear translocator (Gene Name=ARNT)

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