Structure of PDB 5nih Chain B

Receptor sequence
>5nihB (length=260) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL
TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFS
KPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIA
VFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQR
KPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNK
WWYDKGECGS
3D structure
PDB5nih Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
ChainB
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8VE B E13 Y61 P89 T91 R96 L138 G141 S142 T143 E193 M196 E10 Y58 P86 T88 R93 L135 G138 S139 T140 E190 M193 MOAD: Ki=134nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5nih, PDBe:5nih, PDBj:5nih
PDBsum5nih
PubMed28691798
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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