Structure of PDB 5nf5 Chain B

Receptor sequence
>5nf5B (length=255) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYD
VKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFS
KPFMTLGISILYRKGTPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKIS
TYEKMWAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNC
NLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWR
GNGCP
3D structure
PDB5nf5 Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
ChainB
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8VN B Y61 P88 T90 R95 S141 T142 E190 Y59 P86 T88 R93 S139 T140 E188 PDBbind-CN: -logKd/Ki=6.82,Ki=152nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5nf5, PDBe:5nf5, PDBj:5nf5
PDBsum5nf5
PubMed28691798
UniProtP22756|GRIK1_RAT Glutamate receptor ionotropic, kainate 1 (Gene Name=Grik1)

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