Structure of PDB 5nc2 Chain B

Receptor sequence
>5nc2B (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
EQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGRK
IQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFAS
AMMHALEVL
3D structure
PDB5nc2 Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
ChainB
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y16 K22 W23 T30 N71 F77 Q79 R81 V86 Y14 K20 W21 T28 N69 F75 Q77 R79 V84
External links
PDB RCSB:5nc2, PDBe:5nc2, PDBj:5nc2
PDBsum5nc2
PubMed33184177
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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