Structure of PDB 5nbx Chain B

Receptor sequence
>5nbxB (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVV
GRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANV
FASAMMHALEVL
3D structure
PDB5nbx Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
ChainB
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y16 D18 Y17 D19
BS02 peptide B Y16 W23 K69 N71 F77 Q79 R81 Y17 W24 K70 N72 F78 Q80 R82
External links
PDB RCSB:5nbx, PDBe:5nbx, PDBj:5nbx
PDBsum5nbx
PubMed33184177
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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