Structure of PDB 5nbs Chain B

Receptor sequence
>5nbsB (length=841) Species: 367110 (Neurospora crassa OR74A) [Search protein sequence]
LAYSEPHYPSPWMDPKAIGWEEAYEKAKAFVSQLTLLEKVNLTTGIGWGA
EQCVGQTGAIPRLGLKSMCMQDAPLAIRGTDYNSVFPAGVTTAATFDRGL
MYKRGYALGQEAKGKGVTVLLGPVAGPLGRAPEGGRNWEGFSTDPVLTGI
AMAETIKGTQDAGVVACAKHFIGNEQEHFRQVGESQDYGYNISETLSSNI
DDKTMHEMYLWPFVDAIRAGVGSFMCAYTQANNSYSCQNSKLLNNLLKQE
NGFQGFVMSDWQAHHSGVASAAAGLDMSMPGDTMFNSGRSYWGTNLTLAV
LNGTVPQWRIDDMAMRIMAAFFKVGQTVEDQEPINFSFWTLDTYGPLHWA
ARKDYQQINWHVNVQGDHGSLIREIAARGTVLLKNTGSLPLKKPKFLAVI
GEDAGPNPLGPNGCADNRCNNGTLGIGWGSGTGNFPYLVTPDQALQARAV
QDGSRYESVLRNHAPTEIKALVSQQDATAIVFVNANSGEGFIEIDGNKGD
RLNLTLWNEGDALVKNVSSWCNNTIVVLHTPGPVLLTEWYDNPNITAILW
AGMPGQESGNSITDVLYGRVNPSGRTPFTWGATRESYGTDVLYEPNNGNE
APQLDYTEGVFIDYRHFDKANASVLYEFGFGLSYTTFEYSNLKIEKHQVG
EYTPTTGQTEAAPTFGNFSESVEDYVFPAAEFPYVYQFIYPYLNSTDMSA
SSGDAQYGQTAEEFLPPKANDGSAQPLLRSSGLHHPGGNPALYDIMYTVT
ADITNTGKVAGDEVPQLYVSLGGPEDPKVVLRGFDRLRVEPGEKVQFKAV
LTRRDVSSWDTVKQDWVITEYAKKVYVGPSSRKLDLEEVLP
3D structure
PDB5nbs Structural studies of a glycoside hydrolase family 3 beta-glucosidase from the model fungus Neurospora crassa.
ChainB
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.21: beta-glucosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MAN B D370 Y371 Q372 D354 Y355 Q356
BS02 MAN B R745 K829 R729 K813
BS03 MAN B Q254 S282 Q238 S266
BS04 MAN B Q254 F730 L731 P732 Q238 F714 L715 P716
BS05 MAN B Y19 S20 P22 Y3 S4 P6
BS06 MAN B E210 H281 E194 H265
BS07 MAN B H479 A480 P481 T482 E483 H463 A464 P465 T466 E467
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0008422 beta-glucosidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0009251 glucan catabolic process
GO:0030245 cellulose catabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5nbs, PDBe:5nbs, PDBj:5nbs
PDBsum5nbs
PubMed30511673
UniProtQ7RWP2

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