Structure of PDB 5n9c Chain B

Receptor sequence
>5n9cB (length=110) Species: 9606 (Homo sapiens) [Search protein sequence]
SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGR
KIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFA
SAMMHALEVL
3D structure
PDB5n9c Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
ChainB
Resolution1.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y16 W23 K69 N71 F77 Q79 R81 V86 Y15 W22 K68 N70 F76 Q78 R80 V85
BS02 peptide B E3 Y38 R47 R51 N61 E2 Y37 R46 R50 N60
External links
PDB RCSB:5n9c, PDBe:5n9c, PDBj:5n9c
PDBsum5n9c
PubMed33184177
UniProtQ8N8S7|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)

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