Structure of PDB 5n2l Chain B

Receptor sequence
>5n2lB (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
LSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMD
LSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDV
FEFRYAKMP
3D structure
PDB5n2l Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline analogue
ChainB
Resolution1.89 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8J2 B K363 W370 Y373 K18 W25 Y28
BS02 8J2 B W370 P371 F372 N429 H433 V435 W25 P26 F27 N84 H88 V90
External links
PDB RCSB:5n2l, PDBe:5n2l, PDBj:5n2l
PDBsum5n2l
PubMed
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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