Structure of PDB 5n17 Chain B

Receptor sequence
>5n17B (length=130) Species: 5476 (Candida albicans) [Search protein sequence]
AMGAPKPPQEPDMNNLPENPIPQHQAKFVLNTIKAVKRNREAVPFLHPVD
TVKLNVPFYYNYIPRPMDLSTIERKINLKAYEDVSQVVDDFNLMVKNCKK
FNGEAAGISKMATNIQAQFEKLMVKVPPKE
3D structure
PDB5n17 Selective BET bromodomain inhibition as an antifungal therapeutic strategy.
ChainB
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 8FK B P233 V245 F290 N291 P44 V56 F101 N102 MOAD: Kd=4.8uM
External links
PDB RCSB:5n17, PDBe:5n17, PDBj:5n17
PDBsum5n17
PubMed28516956
UniProtQ5A4W8|BDF1_CANAL Bromodomain-containing factor 1 (Gene Name=BDF1)

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