Structure of PDB 5miu Chain B

Receptor sequence
>5miuB (length=447) Species: 10090 (Mus musculus) [Search protein sequence]
PSHVPFLLIGGGTAAFAAARSIRARDPGARVLIVSEDPELPYMRPPLSKE
LWFSDDPNVTKTLQFRQWNKERSIYFQPPSFYVSAQDLPNIENGGVAVLT
GKKVVHLDVRGNMVKLNDGSQITFEKCLIATGGTPRSLSAIDRAGAEVKS
RTTLFRKIGDFRALEKISREVKSITVIGEGFLGSELACALGRKSQASGIE
VIQLFPEKGNMGKILPQYLSNWTMEKVKREGVKVMPNAIVQSVGVSGGRL
LIKLKDGRKVETDHIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQA
RSNIWVAGDAACFYDIKLGRRRVEHHDHAVVSGRLAGENMTGAAKPYWHQ
SMFWSDLGPDVGYEAIGLVDSSLPTVGVFAKATAQDNPKSATEQDYGKGV
IFYLRDKVVVGIVLWNVFNRMPIARKIIKDGEQHEDLNEVAKLFNIH
3D structure
PDB5miu Structural bases of the altered catalytic properties of a pathogenic variant of apoptosis inducing factor.
ChainB
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.6.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G137 G138 G139 A141 E163 R171 P172 K176 K231 V232 T259 R284 D437 H453 H454 A457 F481 W482 G10 G11 G12 A14 E36 R44 P45 K49 K103 V104 T131 R156 D309 H325 H326 A329 F353 W354
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046983 protein dimerization activity

View graph for
Molecular Function
External links
PDB RCSB:5miu, PDBe:5miu, PDBj:5miu
PDBsum5miu
PubMed28666871
UniProtQ9Z0X1|AIFM1_MOUSE Apoptosis-inducing factor 1, mitochondrial (Gene Name=Aifm1)

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