Structure of PDB 5m6b Chain B

Receptor sequence
>5m6bB (length=555) Species: 5341 (Agaricus bisporus) [Search protein sequence]
LLATVGPTGGVKNRLDIVDFVRDEKFFTLYVRALQAIQDKDQADYSSFFQ
LSGIHGLPFTPWAKPKDTPTVPYESGYCTHSQVLFPTWHRVYVSIYEQVL
QEAAKGIAKKFTVHKKEWAQAAEDLRQPYWDTGFALVPPDEIIKLEQVKI
TNYDGTKITVRNPILRYSFHPIDPSFNGYPNFDTWRTTVRNPDADKKENI
PALIAKLDLEADSTREKTYNMLKFNANWEAFSNHGEFDDTHANSLEAVHD
DIHGFVGRGAIRGHMTHALFAAFDPIFWLHHSNVDRHLSLWQALYPGVWV
TQGPEREGSMGFAPGTELNKDSALEPFYETEDKPWTSVPLTDTALLNYSY
PDFDKVKGGTPDLVRDYINDHIDRRYGIKKSEGGKNPALDLLSDFKGVTH
DHNEDLKMFDWTIQASWKKFELDDSFAIIFYFAADGSTNVTKENYIGSIN
IFRGTTPTNCANCRTQDNLVQEGFVHLDRFIARDLDTFDPQAVHRYLKEK
KLSYKVVADDHSVTLKSLRIRVQGRPLHLPPGVSFPRLDKNIPIVNFDDV
LDLVT
3D structure
PDB5m6b Heterologous expression and characterization of functional mushroom tyrosinase (AbPPO4).
ChainB
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.18.1: tyrosinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU B H57 H82 H91 H55 H80 H89
BS02 CU B H251 H255 H283 H249 H253 H281
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0004503 tyrosinase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0042438 melanin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5m6b, PDBe:5m6b, PDBj:5m6b
PDBsum5m6b
PubMed28500345
UniProtC7FF05|PPO4_AGABI Polyphenol oxidase 4 (Gene Name=PPO4)

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