Structure of PDB 5m45 Chain B

Receptor sequence
>5m45B (length=709) Species: 78245 (Xanthobacter autotrophicus Py2) [Search protein sequence]
RNVQVLGIDAGGTMTDTFFVDQDGDFVVGKAQSTPQNEALGLIASSEDGL
ANWGMSLHEALAQLQTGVYSGTAMLNRVVQRKGLKCGLIVNRGMEDFHRM
GRAVQSHLGYAYEDRIHLNTHRYDPPLVPRHLTRGVVERTDMMGTQVIPL
REDTARDAARDLIAADAEGIVISLLHSYKNPVNERRVRDIVLEEVEKSGK
KIPVFASADYYPVRKETHRTNTTILEGYAAEPSRQTLSKISNAFKERGTK
FDFRVMATHGGTISWKAKELARTIVSGPIGGVIGAKYLGEVLGYKNIACS
DIGGTSFDVALITQGEMTIKNDPDMARLVLSLPLVAMDSVGAGAGSFIRL
DPYTRAIKLGPDSAGYRVGVCWKESGIETVTISDCHMVLGYLNPDNFLGG
AVKLDRQRSVDAIKAQIADPLGLSVEDAAAGVIELLDSDLRDYLRSMISG
KGYSPASFVCFSYGGAGPVHTYGYTEGLGFEDVIVPAWAAGFSAFGCAAA
DFEYRYDKSLDINMPTETPDTDKEKAAATLQAAWEELTKNVLEEFKLNGY
SADQVTLQPGYRMQYRGQLNDLEIESPLAQAHTAADWDQLTDAFNATYGR
VYAASARSPELGYSVTGAIMRGMVPIPKPKIPKEPEEGETPPESAKIGTR
KFYRKKRWVDAQLYHMESLRPGNRVMGPAVIESDATTFVVPDGFETWLDG
HRLFHLREV
3D structure
PDB5m45 Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation.
ChainB
Resolution1.87 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.4.1.6: acetone carboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B T21 M22 G311 G312 A352 F405 L406 G473 D692 A693 T694 T695 T13 M14 G303 G304 A344 F397 L398 G465 D684 A685 T686 T687
BS02 MG B M22 D24 M14 D16
BS03 ACT B R123 K459 R115 K451
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016874 ligase activity
GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity
GO:0018710 acetone carboxylase activity
Biological Process
GO:0006749 glutathione metabolic process
GO:0140977 cellular detoxification of acetone
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5m45, PDBe:5m45, PDBj:5m45
PDBsum5m45
PubMed28775283
UniProtQ8RM04|ACXA_XANP2 Acetone carboxylase beta subunit (Gene Name=acxA)

[Back to BioLiP]