Structure of PDB 5lou Chain B

Receptor sequence
>5louB (length=301) Species: 9606 (Homo sapiens) [Search protein sequence]
GLVPRGSHMSCPVQTMDPEVTLLLQCPGGGLPQEQIQAELSPAHDRRPLP
GGDEAITAIWETRLKAQPWLFDAPKFRLHSATLAPIGSRGPQLLLRLGLT
SYRDFLGTNWSSSAAWLRQQGATDWGDTQAYLADPLGVGAALATADDFLV
FLRRSRQVAEAPGLVDVPGGHPEPQALCPGGSPQHQDLAGQLVVHELFSS
VLQEICDEVNLPLLTLSQPLLLGIARNETSAGRASAEFYVQCSLTSEQVR
KHYLSGGPEAHESTGIFFVETQNVQRLLETEMWAELCPSAKGAIILYNRV
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3D structure
PDB5lou Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural Fold.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.45: UDP-sugar diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 B K60 H156 R218 K75 H171 R233
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008768 UDP-sugar diphosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0052751 GDP-mannose hydrolase activity
Cellular Component
GO:0005654 nucleoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:5lou, PDBe:5lou, PDBj:5lou
PDBsum5lou
PubMed29413322
UniProtQ9BRQ3|NUD22_HUMAN Uridine diphosphate glucose pyrophosphatase NUDT22 (Gene Name=NUDT22)

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