Structure of PDB 5lhz Chain B

Receptor sequence
>5lhzB (length=76) Species: 9606 (Homo sapiens) [Search protein sequence]
LLKSVFVKNVGWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTT
RYGENEKLPDYIKQKLQCLSSILLMF
3D structure
PDB5lhz A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies.
ChainB
Resolution2.51 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B V907 Q920 A921 E942 K943 L944 L955 L959 V21 Q34 A35 E56 K57 L58 L69 L73
BS02 peptide B Q950 Q953 C954 S956 S957 L960 Q64 Q67 C68 S70 S71 L74
External links
PDB RCSB:5lhz, PDBe:5lhz, PDBj:5lhz
PDBsum5lhz
PubMed28202467
UniProtO00444|PLK4_HUMAN Serine/threonine-protein kinase PLK4 (Gene Name=PLK4)

[Back to BioLiP]