Structure of PDB 5lfk Chain B

Receptor sequence
>5lfkB (length=236) Species: 562 (Escherichia coli) [Search protein sequence]
QEFLAAGASFNQVVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLR
RRSGESKELERIETEAQRLDSMINDLLVMSRNQLVSETIKANQLWSEVLD
NAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTKI
EVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFYRTDEARDRESGGTGL
GLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLYK
3D structure
PDB5lfk Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase.
ChainB
Resolution3.094 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B N360 Y364 V391 I399 R405 T406 A409 T417 G418 G420 L421 L445 N141 Y145 V172 I180 R186 T187 A190 T198 G199 G201 L202 L226
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5lfk, PDBe:5lfk, PDBj:5lfk
PDBsum5lfk
PubMed28552574
UniProtP0AE82|CPXA_ECOLI Sensor histidine kinase CpxA (Gene Name=cpxA)

[Back to BioLiP]