Structure of PDB 5laa Chain B

Receptor sequence
>5laaB (length=159) Species: 523846 (Methanothermus fervidus DSM 2088) [Search protein sequence]
VKKKEPAEGWPVVSGDYIVGDPESPVAAVTLASHIEDIPIDAGAAIAGPC
KTENLGIEKVIANIISNPNIRFLVLCGSEVQGHIVGQSMKALHKNGVDDK
RKIIGAKGAIPYIENLPEEALERFQKQVEIVDLIDVEDADQIKEKVKECI
EKDPGAFEE
3D structure
PDB5laa MtrA of the sodium ion pumping methyltransferase binds cobalamin in a unique mode.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.86: Transferred entry: 7.2.1.4.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 B12 B G16 D17 Y18 A29 V30 G49 P50 K52 T53 N55 G57 K60 V61 Q82 G83 H84 A110 G15 D16 Y17 A28 V29 G48 P49 K51 T52 N54 G56 K59 V60 Q81 G82 H83 A109
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0030269 tetrahydromethanopterin S-methyltransferase activity
GO:0050897 cobalt ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0006814 sodium ion transport
GO:0015948 methanogenesis
GO:0019386 methanogenesis, from carbon dioxide
GO:0032259 methylation
Cellular Component
GO:0005886 plasma membrane

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Molecular Function

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Cellular Component
External links
PDB RCSB:5laa, PDBe:5laa, PDBj:5laa
PDBsum5laa
PubMed27324530
UniProtE3GWY7

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