Structure of PDB 5la2 Chain B

Receptor sequence

>5la2B (length=465) Species: 1515 (Acetivibrio thermocellus)

SPQRGRPRLNAARTTFVGDNGQPLRGPYTSTEWTAAAPYDQIARVKELGF
NAVHLYAECFDPRYPAPGSKAPGYAVNEIDKIVERTRELGLYLVITIGNG
ANNGNHNAQWARDFWKFYAPRYAKETHVLYEIHNEPVAWGPPYSSSTANP
PGAVDMEIDVYRIIRTYAPETPVLLFSYAVFGGKGGAAEALKDIRAFNKA
VFGNENAVWTNEAVAFHGYAGWQETTIAVEELLKAGYPCFMTSYAGGGLD
VELTYELERLGVSWLTFQYIPPTGVSDDVTKPEYFSALVENSGLSWTPDY
GNWPAARGVYGNGGLARETAGTTRIEAEDFDWGGNGVSYYDTDSVNVGGQ
YRPDEGVDIEKTSDTGGGYNVGWISEGEWLEYTIRVRNPGYYNLSLRVAG
ISGSRVQVSFGNQDKTGVWELPATGGFQTWTTATRQVFLGAGLQKLRINA
LSGGFNLNWIELSPI

3D structure

• PDB: 5la2 The Mechanism by Which Arabinoxylanases Can Recognize Highly Decorated Xylans.
• Chain: B
• Resolution: 1.65 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	XYS	B	N139 N170 E171 Y255 S279 F310	N103 N134 E135 Y219 S243 F267
BS02	XYP	B	W69 A137	W33 A101
BS03	AHR	B	E68 N135 G136 N139 F310	E32 N99 G100 N103 F267
BS04	ARB	B	E411 W424 N507	E360 W373 N456
BS05	CA	B	E377 E379 Y420 N509	E326 E328 Y369 N458
BS06	CA	B	D392 D409 W424 E429	D341 D358 W373 E378
BS07	CA	B	D392 D394 V396 G407 D409	D341 D343 V345 G356 D358

Gene Ontology

Molecular Function

• GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
• GO:0030246 carbohydrate binding

Biological Process

• GO:0000272 polysaccharide catabolic process
• GO:0005975 carbohydrate metabolic process

External links

• PDB: RCSB:5la2, PDBe:5la2, PDBj:5la2
• PDBsum: 5la2
• PubMed: 27531750
• UniProt: A3DHG6