Structure of PDB 5l8a Chain B

Receptor sequence
>5l8aB (length=62) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]
SEREKRVSNAVEFLLDSRVRRTPTSSKVHFLKSKGLSAEEICEAFTKVGQ
PKTLNEIKRILS
3D structure
PDB5l8a Inhibitors of PEX14 disrupt protein import into glycosomes and kill Trypanosoma parasites.
ChainB
Resolution1.57 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6RB B S30 H33 S26 H29 MOAD: Ki=12.3uM
BS02 6RB B N13 F17 R22 T26 F34 K38 N9 F13 R18 T22 F30 K34 MOAD: Ki=12.3uM
Gene Ontology
Biological Process
GO:0016560 protein import into peroxisome matrix, docking
Cellular Component
GO:0005778 peroxisomal membrane

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5l8a, PDBe:5l8a, PDBj:5l8a
PDBsum5l8a
PubMed28360328
UniProtQ8IEW2

[Back to BioLiP]