Structure of PDB 5kyw Chain B

Receptor sequence

>5kywB (length=766) Species: 9606 (Homo sapiens)

AMGSPIQVIENDRASRGGQVYATNTRGQIPPLVTTDCMIQDQGNASPRFI
RCTTYCFPCTSDMAKQAQIPLAAVIKPFATIPSNESPLYLVNHGESGPVR
CNRCKAYMCPFMQFIEGGRRYQCGFCNCVNDVPPFYFQHLDHIGRRLDHY
EKPELSLGSYEYVATLDYCRKSKPPNPPAFIFMIDVSYSNIKNGLVKLIC
EELKTMLEKIPKEEQEETSAIRVGFITYNKVLHFFNVKSNLAQPQMMVVT
DVGEVFVPLLDGFLVNYQESQSVIHNLLDQIPDMFADSNENETVFAPVIQ
AGMEALKAADCPGKLFIFHSSLPTAEAPGKLKNRDDKKLVNTDKEKILFQ
PQTNVYDSLAKDCVAHGCSVTLFLFPSQYVDVASLGLVPQLTGGTLYKYN
NFQMHLDRQQFLNDLRNDIEKKIGFDAIMRVRTSTGFRATDFFGGILMNN
TTDVEMAAIDCDKAVTVEFKHDDKLSEDSGALIQCAVLYTTISGQRRLRI
HNLGLNCSSQLADLYKSCETDALINFFAKSAFKAVLHQPLKVIREILVNQ
TAHMLACYRKNCASPSAASQLILPDSMKVLPVYMNCLLKNCVLLSRPEIS
TDERAYQRQLVMTMGVADSQLFFYPQLLPIHTLDVKSTMLPAAVRCSESR
LSEEGIFLLANGLHMFLWLGVSSPPELIQGIFNVPSFAHINTDMTLLPEV
GNPYSQQLRMIMGIIQQKRPYSMKLTIVKQREQPEMVFRQFLVEDKGGSS
YVDFLCCVHKEICQLL

3D structure

• PDB: 5kyw TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats.
• Chain: B
• Resolution: 3.2 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	B	C364 C386 C389	C101 C123 C126

Gene Ontology

Molecular Function

• GO:0008270 zinc ion binding

Biological Process

• GO:0006886 intracellular protein transport
• GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport

Cellular Component

• GO:0030127 COPII vesicle coat

External links

• PDB: RCSB:5kyw, PDBe:5kyw, PDBj:5kyw
• PDBsum: 5kyw
• PubMed: 27551091
• UniProt: O94855|SC24D_HUMAN Protein transport protein Sec24D (Gene Name=SEC24D)