Structure of PDB 5kw1 Chain B

Receptor sequence
>5kw1B (length=195) Species: 9606 (Homo sapiens) [Search protein sequence]
GSAAQRQGALAIMSRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV
TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPII
DQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSATLARDPTTGK
HKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLL
3D structure
PDB5kw1 Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B Y132 F172 F174 K201 R204 P205 S206 N207 Y17 F57 F59 K86 R89 P90 S91 N92
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5kw1, PDBe:5kw1, PDBj:5kw1
PDBsum5kw1
PubMed33253191
UniProtQ9UHX1|PUF60_HUMAN Poly(U)-binding-splicing factor PUF60 (Gene Name=PUF60)

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