Structure of PDB 5ks1 Chain B

Receptor sequence
>5ks1B (length=397) Species: 216895 (Vibrio vulnificus CMCP6) [Search protein sequence]
GMQKLTILGATGSIGASTLKVIEQNPDKFSVVALAADSNVEKMQQLCQRW
QPEYAVMANKEAALRLKMALAVLAPNTQVLGGQEALCYVATLEQVDSVMA
AIVGAAGLVPTMAAVKAGKRILLANKEALVMSGQLFIDEVEKSGAQLLPV
DSEHNAIFQCLPQTVQGNLGRCDLASQGVSHILLTGSGGPFRYTDVAELE
AVTPEQAIAHPNWSMGPKISVDSATMMNKGLEYIEAKWLFNASRDQLKVI
IHPQSVIHSMVQYLDGSVLAQMGEPDMATPIALTLSYPERVKAGVKPLDF
TQVGELTFLQPDFERYPCLALAIEACYLGQHATTTLNAANEVAVAAFLAR
QIKFTDIARVNDSVLNQVCKQLDSLESLLELDRMARTLADEVVRERA
3D structure
PDB5ks1 Structural characterization of 1-deoxy-D-xylulose 5-phosphate Reductoisomerase from Vibrio vulnificus.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.267: 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 B G185 S186 K228 G186 S187 K229
BS02 MN B E152 E231 E153 E232
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0030145 manganese ion binding
GO:0030604 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GO:0046872 metal ion binding
GO:0070402 NADPH binding
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
GO:0051484 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5ks1, PDBe:5ks1, PDBj:5ks1
PDBsum5ks1
PubMed30278288
UniProtQ8DBF5|DXR_VIBVU 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Gene Name=dxr)

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