Structure of PDB 5kro Chain B

Receptor sequence
>5kroB (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKCKNVPLSDLLLEMLDAH
3D structure
PDB5kro Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 E380 D538 L539 E542 I52 K56 L66 V70 L73 E74 D219 L220 E223
BS02 6WW B E353 L387 M421 H524 L525 E47 L81 M112 H206 L207
External links
PDB RCSB:5kro, PDBe:5kro, PDBj:5kro
PDBsum5kro
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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