Structure of PDB 5krl Chain B

Receptor sequence
>5krlB (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEPFSEASMMGLLTNLADRELVHMIN
WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLL
LDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSN
KGMEHLYSMKCKNVPLSDLLLEMLDAHR
3D structure
PDB5krl Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 V376 L379 D538 E542 I49 V67 L70 D218 E222
BS02 6WR B E353 H524 E44 H205
External links
PDB RCSB:5krl, PDBe:5krl, PDBj:5krl
PDBsum5krl
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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