Structure of PDB 5krj Chain B

Receptor sequence
>5krjB (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
LALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELV
HMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFA
PNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLN
SGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMPLSDLLLEMLDAHR
3D structure
PDB5krj Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 L372 V376 L379 E380 D538 E542 I53 K57 L67 V71 L74 E75 D219 E223
BS02 6WP B M343 L346 T347 E353 M388 L391 F404 M421 I424 H524 L525 M38 L41 T42 E48 M83 L86 F99 M116 I119 H211 L212
External links
PDB RCSB:5krj, PDBe:5krj, PDBj:5krj
PDBsum5krj
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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