Structure of PDB 5kq4 Chain B

Receptor sequence
>5kq4B (length=242) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence]
GGSMSFTNATFSQVLDDLSARFILNLPAEEQSSVERLCFQIEQAHWFYED
FIRAQNDQLPSLGLRVFSAKLFAHCPLLWKWSKVHEEAFDDFLRYKTRIP
VRGAIMLDMSMQQCVLVKGWKASSGWGFPKGKIDKDESDVDCAIREVYEE
TGFDCSSRINPNEFIDMTIRGQNVRLYIIPGISLDTRFESRTRKEISKIE
WHNLMDLPTFKKNKPQTMKNKFYMVIPFLAPLKKWIKKRNIA
3D structure
PDB5kq4 Structural basis of mRNA-cap recognition by Dcp1-Dcp2.
ChainB
Resolution2.56 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6VQ B W43 D47 D88 Y92 K93 R95 K127 R167 Y220 W46 D50 D91 Y95 K96 R98 K130 R170 Y223
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0016787 hydrolase activity
GO:0030145 manganese ion binding
GO:0140933 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
Biological Process
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA

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Molecular Function
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Biological Process
External links
PDB RCSB:5kq4, PDBe:5kq4, PDBj:5kq4
PDBsum5kq4
PubMed27694842
UniProtO13828|DCP2_SCHPO mRNA decapping complex subunit 2 (Gene Name=dcp2)

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