Structure of PDB 5ko7 Chain B

Receptor sequence
>5ko7B (length=200) Species: 760192 (Haliscomenobacter hydrossis DSM 1100) [Search protein sequence]
PAFIPYAGAQFEPEEMLSKSAEYYQFMDHRRTVREFSNRAIPLEVIENIV
MTASTAPSGAHKQPWTFVVVSDPQIKAKIRQAAEKEEFESHKPFLEIAPY
LIVVFRKAYDVLPDGTQRKNYYVQESVGIACGFLLAAIHQAGLVALTHTP
SPMNFLQKILQRPENERPFLLVPVGYPAEGAMVPDLQRKDKAAVMVVYHH
3D structure
PDB5ko7 Active Site Binding Is Not Sufficient for Reductive Deiodination by Iodotyrosine Deiodinase.
ChainB
Resolution2.248 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.21.1.1: iodotyrosine deiodinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FMN B P61 S62 P57 S58
BS02 FMN B R34 R35 T36 R38 T171 H172 T173 L210 R30 R31 T32 R34 T147 H148 T149 L186
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0140616 iodotyrosine deiodinase activity

View graph for
Molecular Function
External links
PDB RCSB:5ko7, PDBe:5ko7, PDBj:5ko7
PDBsum5ko7
PubMed28157283
UniProtF4KU78|IYD_HALH1 Iodotyrosine deiodinase (Gene Name=IYD)

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