Structure of PDB 5knc Chain B

Receptor sequence
>5kncB (length=588) Species: 768486 (Enterococcus hirae ATCC 9790) [Search protein sequence]
GMQIGKIIKVSGPLVMAENMSEASIQDMCLVGDLGVIGEIIEMRQDVASI
QVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEVTQ
SNFLGRGVQLPALDHEKQWWFEATIEEGTEVSAGDIIGYVDETKIIQHKI
MVPNGIKGTVQKIESGSFTIDDPICVIETEQGLKELTMMQKWPVRRGRPI
KQKLNPDVPMITGQRVIDTFFPVTKGGAAAVPGPFGAGKTVVQHQIAKWS
DVDLVVYVGCGERGNEMTDVVNEFPELIDPNTGESLMERTVLIANTSNMP
VAAREASIYTGITIAEYFRDMGYDVAIMADSTSRWAEALREMSGRLEEMP
GDEGYPAYLGSRLAEYYERSGRVIALGSDQREGSITAISAVSPSGGDISE
PVTQNTLRVVKVFWGLDSSLAQKRHFPSINWIQSYSLYSTEVGRYMDQIL
QQDWSDMVTEGMRILQEEEQLNEIVRLVGIDSLSDNDRLTLEVAKSIRED
YLQQNAFDDVDTFTSREKQFNMLKVILTFGKEARKALSLGAYFNEIMEGT
VAVRERISRSKYIPEEELAKISSINEEIKETIQLIVSE
3D structure
PDB5knc Crystal structures of the ATP-binding and ADP-release dwells of the V1 rotary motor
ChainB
Resolution3.015 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K238 E261 R262 L436
Catalytic site (residue number reindexed from 1) K239 E262 R263 L437
Enzyme Commision number 7.2.2.1: Na(+)-transporting two-sector ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B G235 A236 G237 K238 T239 V240 F425 A505 F506 G236 A237 G238 K239 T240 V241 F426 A506 F507
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046932 sodium-transporting ATP synthase activity, rotational mechanism
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
GO:0046961 proton-transporting ATPase activity, rotational mechanism
GO:0046962 sodium-transporting ATPase activity, rotational mechanism
Biological Process
GO:0006814 sodium ion transport
GO:0035725 sodium ion transmembrane transport
GO:0042777 proton motive force-driven plasma membrane ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport
Cellular Component
GO:0045259 proton-transporting ATP synthase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5knc, PDBe:5knc, PDBj:5knc
PDBsum5knc
PubMed27807367
UniProtQ08636|NTPA_ENTHA V-type sodium ATPase catalytic subunit A (Gene Name=ntpA)

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