Structure of PDB 5km9 Chain B

Receptor sequence
>5km9B (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
APTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRIS
QAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIH
VLGGRQLQWPPG
3D structure
PDB5km9 A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides.
ChainB
Resolution1.45 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.9.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADN B D80 V81 V145 D29 V30 V94 PDBbind-CN: -logKd/Ki=4.25,Kd=55.9uM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:5km9, PDBe:5km9, PDBj:5km9
PDBsum5km9
PubMed28968488
UniProtQ9BX68|HINT2_HUMAN Adenosine 5'-monophosphoramidase HINT2 (Gene Name=HINT2)

[Back to BioLiP]