Structure of PDB 5km5 Chain B

Receptor sequence
>5km5B (length=112) Species: 9606 (Homo sapiens) [Search protein sequence]
APTIFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRIS
QAEEEDQQLLGHLLLVAKQTAKAEGLGDGYRLVINDGKLGAQSVYHLHIH
VLGGRQLQWPPG
3D structure
PDB5km5 A Crystal Structure Based Guide to the Design of Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) Activated ProTides.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.9.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 TR5 B L64 F78 D80 V81 N136 S144 V145 H149 H151 L13 F27 D29 V30 N85 S93 V94 H98 H100 PDBbind-CN: -logKd/Ki=6.92,Kd=0.121uM
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:5km5, PDBe:5km5, PDBj:5km5
PDBsum5km5
PubMed28968488
UniProtQ9BX68|HINT2_HUMAN Adenosine 5'-monophosphoramidase HINT2 (Gene Name=HINT2)

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