Structure of PDB 5kgp Chain B

Receptor sequence

>5kgpB (length=316) Species: 272562 (Clostridium acetobutylicum ATCC 824)

MEIKETYDFSSIVDLWNKNIGTVYPMNLELFKQNYINDRQRKKIMGAFNG
EILIGFVIYKQWTYKSGSLKPNHKIGYINSIIVDINFRHQGIGTKLLDAA
EEELINSGVKILRCGSDTYHFFPGIPLECLPSEEFFLVRGYKMQDYFYDL
IGDVSKVDFKKPSIKDGFKVNVMKPEDRKGLFEFLEKSFSGRWLEEFIEF
FQVGMKERDIVLIKYKTSVIGFSHIYDNKSSFIGPPIYWKALLGHNYGGL
GPIGIDKTYRKQGLGRLLLYESLQILKKREVKKMVIDWTEKDIINFYGRF
NFMPWKAYRKATKEVK

3D structure

• PDB: 5kgp Structural Studies on a Glucosamine/Glucosaminide N-Acetyltransferase.
• Chain: B
• Resolution: 1.8 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	PA1	B	W288 E290	W288 E290
BS02	GCS	B	R192 W193 E196 G251 P252 D287 W288	R192 W193 E196 G251 P252 D287 W288
BS03	ACO	B	S80 I81 I82 V83 R88 H89 Q90 G91 G93 T94 C129 S132 F135 R139	S80 I81 I82 V83 R88 H89 Q90 G91 G93 T94 C129 S132 F135 R139	MOAD: Ki=3uM
BS04	COA	B	G254 R260 K261 G263 G265 R266	G254 R260 K261 G263 G265 R266

Gene Ontology

Molecular Function

• GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups

External links

• PDB: RCSB:5kgp, PDBe:5kgp, PDBj:5kgp
• PDBsum: 5kgp
• PubMed: 27348258
• UniProt: Q97ML2