Structure of PDB 5k0a Chain B

Receptor sequence

>5k0aB (length=321) Species: 1111708 (Synechocystis sp. PCC 6803 substr. Kazusa) [Search protein sequence]

KNLDARLDTVYDAIVLGGGMGGLSAAIYLARYGLKCLVVEKGRGRSFWMQ
DLRNYVGLDPDTPGRDIITHSTQQALHWGADLLRGYVEDVTDEGDTLAVK
VKVGKKDSLYPIFRTKYVIAATGIIDNLPQLEDMQNVYDYAGYTLHVCMI
CDGFDMWDQKAVLIAGTEGQINAAFVLNWFTPYITVLTHGLCTVGDEMKA
KLADHGYPLHEAAITKFLGEDHKMSGVELVDGTVMEATTGLINMGSVYHN
HYLKGIEGLEWDGENLVTNDMAQTSHPRIFALGDLKKGLNQVSVAVADGT
LAATQIWRNIRRASEPRKWIH

3D structure

PDB

5k0a Unprecedented pathway of reducing equivalents in a diflavin-linked disulfide oxidoreductase.

Chain

Resolution

1.706 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	B	G28 M29 G30 E49 K50 G53 R54 S55 M58 L61 R62 N63 Y95 V96 A130 T131 V156 C160 H258 D293 Q300 V301	G19 M20 G21 E40 K41 G44 R45 S46 M49 L52 R53 N54 Y86 V87 A121 T122 V147 C151 H249 D284 Q291 V292
BS02	FAD	B	K50 W57 Y95 K111 G113 K114 L137 Y147 A150	K41 W48 Y86 K102 G104 K105 L128 Y138 A141

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0004791	thioredoxin-disulfide reductase (NADPH) activity
GO:0016491	oxidoreductase activity

	Biological Process
GO:0045454	cell redox homeostasis
GO:0098869	cellular oxidant detoxification

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:5k0a, PDBe:5k0a, PDBj:5k0a
PDBsum	5k0a
PubMed	29133410
UniProt	P74746

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