Structure of PDB 5jty Chain B

Receptor sequence
>5jtyB (length=276) Species: 10116 (Rattus norvegicus) [Search protein sequence]
DNHLSIVTLEEAPFVIVEDIDPLTETCVRNTVPCRKFVKINNSTNEGMNV
KKCCKGFCIDILKKLSRTVKFTYDLYLVTNGKHGKKVNNVWNGMIGEVVY
QRAVMAVGSLTINEERSEVVDFSVPFVETGISVMVSRGTQVTGLSDKKFQ
RPHDYSPPFRFGTVPNGSTERNIRNNYPYMHQYMTRFNQRGVEDALVSLK
TGKLDAFIYDAAVLNYKAGRDEGCKLVTIGIFATTGYGIALQKGSPWKRQ
IDLALLQFVGDGEMEELETLWLTGIC
3D structure
PDB5jty Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.
ChainB
Resolution2.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 6ND B V129 P130 F131 V132 E133 V267 M272 E276 L280 V124 P125 F126 V127 E128 V259 M264 E268 L272
BS02 GLU B H88 S114 T116 R121 G172 S173 T174 Y214 D215 H83 S109 T111 R116 G167 S168 T169 Y209 D210
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5jty, PDBe:5jty, PDBj:5jty
PDBsum5jty
PubMed27618671
UniProtQ00959|NMDE1_RAT Glutamate receptor ionotropic, NMDA 2A (Gene Name=Grin2a)

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