Structure of PDB 5jr6 Chain B

Receptor sequence
>5jr6B (length=545) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
VYILINSDEHNSEIINEKDKKIADGILIVRISRIDNRDEIFETIIAFDGK
NTSVVFYEKLRKALLNAYPKIVEKIFLVLEKSLVYPVNNKTLYIHDRKYN
GACAGEKIDKLKQSLMYDIKNVDNLLLSELDEIAYLLNLRGYDYQYSPLF
YSYLLFQFDRQDFSKIVFFTTVKNLPADVKNLLEINKVIVKEYEEIVPYL
RDVVIPSIDFKKYDISLSPYINLMIYKLFDRKNVLLQNSPVVKMKAVKND
VEIDNMKQAHILDGLALLQFFHWCEQKRKTKELFNETEMSLRHKVDYFRS
TKKNFIFPSFSTISASGPNAAVIHYECDKTNATIKPAIYLLDSGGQYLHG
TTDVTRTTHFGEPTAEEKRIYTLVLKGHLRLRKVIFASYTNSSALDFIAR
ENLFNNFMDYNHGTGHGVGLTLNVHEGGCSIGPVGGAPLKKNMVLSNEPG
YYMKDKFGVRIENMQYVISKEITDTTEYLSFDDLTMYPYEKKLLDFSLLT
NQEIKELNEYHTTIRNTLLPLVKQSPQEYGESVEKYLIEITEPIA
3D structure
PDB5jr6 Structure and substrate fingerprint of aminopeptidase P from Plasmodium falciparum.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.11.9: Xaa-Pro aminopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN B D581 H644 S674 E676 E690 D353 H416 S446 E448 E462
BS02 MN B D570 D581 E690 D342 D353 E462
Gene Ontology
Molecular Function
GO:0070006 metalloaminopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:5jr6, PDBe:5jr6, PDBj:5jr6
PDBsum5jr6
PubMed27462122
UniProtA0A144A2H0|AMPP_PLAF7 Aminopeptidase P (Gene Name=APP)

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